Jobs

For PhD candidates:
At the ESI, we aim at recruiting PhD students primarily through the International Max Planck Research School for Neural Circuits. Applications outside this program are also welcome at any time and should be sent directly to the head of the lab in which the PhD candidate wishes to work.

For Postdoc candidates:
Applications for postdoc positions are welcome at any time and should be sent directly to the head of the lab in which the postdoc candidate wishes to work.

Virus targeting for cell-type specific optogenetics in non-transgenic animals

The ESI is a research institute in Frankfurt (Main) with the format of a Max Planck Institute (www.esi-frankfurt.de). ESI investigates mechanisms behind human cognition. Because access to the human brain is restricted, approaches in humans are combined with approaches in animals. A key technique is optogenetics, the light-mediated control of neurons through the expression of Channelrhodopsin. Expression is ideally confined to prespecified neuronal cell types, but good cell-type specificity is currently limited to transgenic mouse lines. Yet, understanding the human brain requires research in non-human primates (NHPs), as is performed at ESI. Currently, no transgenic NHP lines exist for cell-type specific optogenetics. To overcome this limitation, this PhD project will target gene delivery to specific neuronal subtypes through engineered viral vectors that selectively infect the targeted subtypes. To achieve this, the Fries lab at ESI collaborates with the Buchholz lab at the Paul-Ehrlich-Institut (PEI) in Langen (Hessen). The Buchholz lab has extensive expertise in the area of virus targeting. ESI and PEI provide outstanding infrastructure.

 

The ideal candidate has experience in biochemistry, molecular genetics or related fields. He/She will work at PEI, for viral vector generation, and at ESI, for vector testing. Testing will be done in mice and rats, and ultimately in NHPs. The contract will be with ESI, for four years, funded directly by ESI. Applications should include a motivation letter, a CV, copies of the school leaving exam and university degrees, lists of university courses with obtained grades, and the names of two scientists, who can provide references (do not include reference letters). The start date is flexible between now and any time in 2019. Please send your application in PDF format to: hr@esi@esi-frankfurt.de 

Open PhD position (m/f)

 Beginning in Mai 2018, the Ernst Struengmann Institute offers a PhD position for initially 3 years in the project:
"Analysis of individual information processing in epileptic and physiologic cognitive cortical networks"
funded by a LOEWE grant (Center for Personalized Translational Epilepsy Research). The successful applicant will analyze magnetoencephalography and intracortical EEG recordings from epilepsy patients using dynamical systems and information theory approaches. Our interdisciplinary group includes Prof. Wolf Singer (ESI), Michael Wibral (BIC), Lucia Melloni (MPIEA), and Christian Kell (GU) and offers access to rare neural data, expertise in data processing, and a creative and cooperative work environment that we judge important for a successful PhD.
We are seeking for an enthusiastic thesis student with interest in the Neurosciences who has skills in data analysis and Matlab programming. He/she should have a background in Natural or Applied Science or Psychology.
Electronic applications (no original documents) are requested until April 1st,  2018 and should be addressed to: Prof. Dr. Wolf Singer (Wolf.Singer@esi-frankfurt.de) Further Information are available here: www.esi-frankfurt.de