ESI TALKS: Bradley Voytek

At this bi-weekly event, we invite speakers from Neuroscience and related fields to share their current research in an informal and casual environment. The ESITALKS last around 45 minutes, followed by discussions.

We are very happy to invite you to this ESITALKS about

The physiology and function of aperiodic neural activity

Perception, action, and cognition depend upon coordinated neural activity. This coordination operates within noisy, distributed neural networks, which themselves change with development, aging, and disease. Extensive field potential and EEG research show that neural oscillations interact with neuronal spiking, suggesting that these interactions could be a mechanism for implementing dynamic coordination between brain regions. These observations have placed oscillations at the forefront of neuroscience research. Our work challenges our conception of what an oscillation even is. Beginning from basic theory and modeling, we show that traditional analyses conflate non-oscillatory, aperiodic activity with oscillations. To prove this, we leverage neural modeling and breadth of empirical data — spanning human iPSC-derived cortical organoids, animal electrophysiology, invasive human EEG, and large-scale data mining. We show that, while not all things that appear oscillatory are so, the physiological information we can extract from the local field potential and EEG may nevertheless be far richer than previously thought, including the nonsinusoidality of oscillation waveform shape and the aperiodic signal.

To register for the upcoming session of ESITALKS please send an email to one of the hosts: nisa.cuevas(at)esi-frankfurt.de, farzad.ziaie(at)esi-frankfurt.de or marius.schneider(at)esi-frankfurt.de.

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